“Threads of Life, Love, & Loss: An HIV/AIDS Story” is a collaboration between the Cornell Fashion + Textile Collection and the Human Sexuality Collection that will be part of the Cornell University Library’s “Threads of History: Textiles at Cornell” exhibitions and the 2022 Cornell Biennial. This fashion exhibit explores how dress, textiles, and archives can be activated in the struggle for health equity amidst on ongoing global health crisis that has lasted more than 40 years and robbed families, friends, and communities of upwards of 40 million lives. We focus on one story of many affected by the HIV/AIDS pandemic, Mark Goldstaub (1951 - 1988), his partner Edmund Wojcik (1955 - 1995) and the many lives they touched, to show how cloth and creative expression have the transformative potential to raise awareness, record histories, memorialize, destigmatize, and make positive change in the world. Garments, quilts, accessories, historical documents, photographs, music composed by Paul Goldstaub, and documentary films by Denise N. Green are included in the display. Exhibition curated by Denise N. Green (Cornell Fashion + Textile Collection, College of Human Ecology) Michael Mamp (Department of Textiles, Apparel Design and Merchandising, Louisiana State University) and Brenda Marston (Human Sexuality Collection, Cornell University Library). Funded in part by the Laurie Conrad Music and Arts Fund of Community Foundation of Tompkins County, Cornell Council for the Arts, Department of Human Centered Design, College of Human Ecology, Cornell University Library, and the Cornell Fashion + Textile Collection.